Rauwolscine: Mother Nature's Fat-Burner

by Matt Theis January 17, 2016

Rauwolscine: Mother Nature's Fat-Burner

If you've taken a lot of pre-workouts or fat-burners, you may have encountered Rauwolscine before.  

Also known as Alpha-Yohimbine, Rauwolscine can be found in a wide variety of different supplements--mostly fat-burners and pre-workout supplements--in either pure (HCl) form or as an extract.

Rauwolscine HCl, or pure Rauwolscine, has a chemical structure that looks like this:

Rauwolscine HCl

Most Rauwolscine supplements, however, are not Rauwolscine HCl but are instead herbal extracts that are supposedly standardized for Rauwolscine content.

The most commonly used plants for Rauwolscine extraction are:

  • Rauvolfia serpentina (A.K.A. Indian Snakeroot)
  • Rauvolfia Vomitoria (A.K.A. The Poison Devil's Pepper)
  • Pausinystalia yohimbe (A.K.A. Yohimbe)

Because Rauwolscine is so closely related to Yohimbine, and found in many of the same species of plants, it often appears alongside Yohimbine in fat-burners and pre-workout supplements.  

This isn't because the two are considered synergistic, it's really just that when it comes to using plant extracts, it can be difficult to isolate individual compounds so many supplement companies just use both in the form of an extract from one of the above plant species.

Unfortunately, such extracts often contain compounds that aren't listed on the label or, at the very least, differing amounts than the amounts listed on the label.

That's why it's better to go with a pure form of Rauwolscine such as Rauwolscine HCl, but more on that later...

Now that we understand what Rauwolscine is and where it comes from, let's talk about how it works.

How Rauwolscine Works

Rauwolscine is an alpha-receptor antagonist, meaning it can inhibit (block) the action of the receptors responsible for stopping lipolysis (fat breakdown).


The result:  You burn considerably more fat during exercise than you normally would be able to.

You see, alpha receptors have a counterpart, known as beta-receptors.  Beta-receptors initiate lipolysis, and alpha receptors stop it.  Think of these receptors as the "yin and yang" of the body's fat-burning controls, regulating the process so that a steady amount of fat is burned, but not too much.

But what is too much, right?  Sure, these receptors served an important evolutionary purpose in human beings when we were running around the forest (or jungle), hunting, running from predators, and going days at a time without eating.  

Beta-receptors made sure our bodies had plenty of substrate (fat) to be burned for energy and alpha receptors stopped us from burning too much, since not having a lot of stored fat could easily be the death of us.

However, as humans evolved and figured out permanent solutions to these problems, these alpha receptors still put a stop to lipolysis, forcing us to conserve more fat than we might actually want to.  

Whether you play competitive sports, body build, or just want to look good, you don't want alpha-receptors to put a stop to fat-loss.

That's where Rauwolscine comes in.  Taking Rauwolscine before you train allows your body to keep breaking down fat beyond the point in exercise where it would normally stop.

What About Yohimbine Though?  Doesn't It Burn Fat Pretty Well?

Yohimbine is absolutely an effective fat-burner when combined with exercise.  It has been shown to induce some pretty significant weight-loss in a relatively small time-frame (2 weeks).  

However, preliminary research indicates Rauwolscine is actually much more potent.

Recall from above that Rauwolscine and Yohimbine are quite similar in terms of function.  Yohimbine, if anything, is more common because it is cheaper and usually comes in the form of a plant extract.

Rauwolscine is actually more potent than Yohimbine and requires a much lower dose to acheive similar effects, but there's another important reason to choose Rauwolscine over Yohimbine supplements...

A 2016 study which tested the amounts of Yohimbine in Yohimbe Extract supplements and found that only 2 out of 49 different supplements (all from different brands) contained the amount of Yohimbine stated on the label.

In other words, supplements that claim to contain a certain amount of Yohimbine simply can't be trusted...

At Singular Sport, we take that a step further by subjecting all batches of finished product to Third Party Testing from an independent lab.  That way, you can actually BE SURE that what we say is in the product is actually in the product.

Here's an example:

Of course, most supplement companies aren't willing to shell out the money for this level of chemical analysis, especially when most of their customers don't realize how important Third Party Testing really is.

Without it, there's really no way to be sure that you're getting what you pay for.

Rauwolscine Comes With Less Side Effects

Yohimbine is notorious for causing some pretty nasty side effects...  

It is often the reason why people react poorly to pre-workouts and fat-burners and is hard to accurately measure when used in the form of an extract.  

Some of the side effects associated withYohimbine are:

  • racing heart beat
  • headaches
  • jitters
  • dizziness
  • nausea

Since Rauwolscine requires a much lower dose to induce similar fat-burning effects, it is much less likely to cause these sorts of negative side effects.  

Rauwolscine HCL is also much safer than Rauwolscine derived from some sort of plant extract because, as stated above, plant extracts often contain unknown bioactives and/or unknown quantities of those bioactives.

How Much Rauwolscine To Take

Rauwolscine is quite potent at just 1 or 2mg doses.  This might come as quite a surprise to some people, but make no mistake, 1-2mg is all you need.  

In some cases, when individual sensitivity is low, 3mg may be used, but jumping to such a high dose right away is not recommended.  Start low, then work your way up.

Most likely, you'll find your "sweet spot" between 1 and 3mg.  That is, the dose at which you can feel it working but it's not overwhelming or anything.

Is Rauwolscine Safe?

There is no scientific research to suggest that Rauwolscine is inherently dangerous, nor is there any reason to believe that it is when used responsibly.  

The key is really measuring the dose.  

Herbal Extracts which claim to be standardized for a certain amount often differ quite drastically from what is presented on the label.  

For that reason, it makes more sense to go with a pure form such as Rauwolscine HCL, not an extract which contains questionable amounts and may also contain other stimulant compounds not listed on the label.

Can Rauwolscine Be Stacked?

Rauwolscine can be combined with other supplements, but caution should exercised when combining it with other stimulant compounds.

There are a few other supplements that can enhance the fat-burning effects of Rauwolwscine:

Caffeine can potentially enhance the fat-burning effects of Rauwolscine, causing you to burn even more fat during your workout, but this level of stimulation may be uncomfortable for those who are sensitive to stimulants, so be careful when stacking!

Higenamine and Synephrine are potentially pretty synergistic with Rauwolscine.

Rauwolscine is an alpha-receptor antagonist and Higenamine and Synephrine are both beta-receptor agonists.  This is the basic model that many stimulant-based fat-burners follow because, well, it works!  

The combination of a beta-agonist and an alpha-antagonist can be a powerful thing when it comes to burning fat.

The Bottom Line

Don't feed into the hype of so called "miracle" weight-loss pills, just follow the science...

Rauwolscine is worth considering by anyone looking to maximize the amount of fat-loss that occurs during training, but remember...

Rauwolscine doesn't magically burn fat.  Nothing does!  With Rauwolscine, you have to still put in the work, but assuming you're willing to do that, it can be VERY effective in a relatively short period of time.

If you work out on a regular basis, and use Rauwolscine prior to training, you WILL burn fat much faster.


Singular Sport Rauwolscine is the only Rauwolscine supplement that contains pure Rauwolscine HCl and is Third Party Tested for purity, label accuracy, and potential contaminants.

In other words, this is the only Rauwolscine supplements you can be sure is actually trustworthy.

Check it out here or on Amazon

Matt Theis
Matt Theis


Hi! I'm Matt Theis, Founder of Singular Sport and Co-Founder/CEO of Momentum Nutrition. When it comes to training, nutrition, supplementation, and all things fitness-related, I believe following the science is the ONLY way to go. If you can't show me the research, I don't believe you!

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